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Metformin, a prescription-based medication, is often prescribed for individuals with high blood sugar caused by type 2 diabetes or gestational diabetes

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When the drug is removed, a big risk is weight regain without re-building muscle, worsening insulin resistance and leaving the patient with a condition called sarcopenic obesity potentially worse off than prior to taking the GLP-1

Wurtman R

For reference data, see the peptide half-life chart